Did This Study Actually Take Place Yeilding These Results?

Question by dodo d: Did this study actually take place yeilding these results?
In order to understand the complex workings of the immune system, scientists build mathematical models to explain the progression of disease and the body’s response to it. Researchers at Michigan State University, in East Lansing, and Marquette University, in Milwaukee, created a model that replicates what is thought to occur during the initial stages of HIV infection. Based on their model, they believe that the human body can successfully rid itself of the HIV virus, unless other cofactors are attacking the immune system at the same time. Immune-weakening cofactors include such things as malnutrition, infectious agents (e.g., cytomegalovirus, a member of the herpes family), drugs, parasites, etc.

Best answer:

Answer by nobodyinparticular
The information you give does not describe a clinical study. It describes the creation of a mathematical model. In other words, it is a theory. It is also a ten-year-old theory, and in the study of HIV, ten years is a long time.

The paper describing this model was published in the Journal of Theoretical Biology in 1997. The following is the abstract:

“J Theor Biol. 1997 Jul 7;187(1):135-46.
The necessity of cofactors in the pathogenesis of AIDS: a mathematical model.

Root-Bernstein RS, Merrill SJ.
Department of Physiology, Michigan State University, East Lansing, MI, 48824-1101, USA.

Current arguments for the role of cofactors in the initiation of a chronic HIV infection and progression of AIDS are given. The natural history of an HIV infection as affected by cofactors which provide additional stimulatory signals is explored through a mathematical model. The model demonstrates that “antigen load” plays a role in determining susceptibility to an HIV infection. It also suggests that certain individuals may not be able to be infected by small doses of HIV and that the identification and treatment of existing cofactors may be useful in treating early stages of HIV infection. Prevention of cofactor exposures may also protect against HIV infection.”

Answer by 9837591703947
yeh, make since to me, the body is a maracules machine, the immune system is amazing but it cant take on too much

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